Hello,
Sorry to hear you are having issues. Please try purge and reinstall steps as mentioned here: https://forums.stardock.com/488142/groupy-support-faq#reinstalling. Just make sure to re-download the latest version from your account. Reboot after the purged. Reinstall, and Reboot again after the installation. Retest it. Report back here.

Thank you,

Basj,
Stardock Community Assistant.

My issue started when I thought I was having issues with combining my different windows. Note that I said though I will explain shortly.

mySystem
NVIDIA GeForce GTX 670M
Screen Resolution 1920x1080
Memory 16GB
Windows 10 Pro 64bit, 10.0.1904 to Build 19042
Asus G75VW Portable
Groupy 1.49.1
Chrome 92.0.4515.159
Fence 3.1.3.3
Directory Opus 12.24 64 bit
Nuance Dragon 15.61
Microsoft OneNote  365
DisplayFusion Pro 9.8
SnagIt 2021.4.3 64bit

All the above are installed and used daily with StarDock -  Groupy & Fence.

Now for the cure to the issue, I was having.

1. Download the most recent version of Groupy.
2. Download GroupyPurge http://sd.stardock.com/Support/uploads/groupyPurge.zip
3. Place GroupyPurge on desktop.
4. Left-Click GroupPurge. StarDock instructions call for a right-click and then use Run as Administrator. I did not have a Run as    Administrator when I did the right-click so I did the left click with success. After it ran I did a reboot and all was successful.

As I mentioned above I'm not sure that I really had an issue. I was playing around with the settings in Groupy and then my problem began. But I believe what actually happened, I changed the delay settings for placing a window. I can now automatically group my primary program called Directory Opus. Before I had to manually place Opus into a group. My group consists of four windows, Microsoft-OneNote, Nuance-Dragon, Chrome, and Directory Opus.

mySetting
Visuals
Position the Tabs - Combine if Possible
Yes-Only show a close button on the active tab
No-Show a close icon on tabs
No-Tab bar should extend to full window width.

Settings
Yes-Always group windows when moved on top of each other
Yes-Instantly group windows
Yes-Enable hotkeys to switch between tabs in the group (A middle-click on a tab should do nothing)

Applications Grouping
dopus.exe (I entered in Automatic Group Box) Used in conjunction with Directory Opus.
I did not use this before. This addition might be the reason why Opus is now loading with Groupy without any issues.

Advanced
Yes-Open new blank document in Word/Excel rather than recent documents (I never use it)

I list all this information to help you understand that Groupy works with just about anything. When combined with he rest of my system any-any information is instantly in front of my eyes, and by voice.
Example:
I Say Today (The above Groupy I saved at the end of yesterday is in front of me.
I Say OneNote Shortcut - I'm looking right at my Shorcuts for OneNote.

Groupy gives me the ability to mix and match my different programs in one convenient tabbed group just by Saying Open ??? it's right in front of me. Combining it with StarDock-Fences organizes it with a DeskTop Folder and as a DeskTop item, I can open it with a verbal command. Groupy where have you been for the last 30 years?

All for now and back to work.
Have a great day

Bob